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Dr. Mukesh Chandrabhan Agrawal

Professor & HOD at K J Somaiya Medical College and Research Centre
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  • Department:
    Pediatrics
  • Institute:
    K J Somaiya Medical College and Research Centre
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    mukesh.a@somaiya.edu

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Introduction

Dr Mukesh Agrawal has over 40 years of experience in the field of Pediatrics, including teaching and training of  undergraduate and postygraduate medical students. He has wide experencie in the field of General pediatrics, Respiratory disorders and infectious diseases in children and adolescents. 

He has over 80 national and international reserarch publications and over 200 research presentations in various  international and national conferences. He has authored six books on Pediatrics , including widely acclaimed Textbook of Pediatrtics and Immunizations in children. He has been the guest speaker for many national and international conferences, including orations.

He has vast experience in research and clinical trials, including those sponsored by Governmental bodies and Industries.

He has been the ex-member of National Immunization Committee of IAP, as well as Chairperson of AEFI committee for Mumbai city during 2014-2022, including  that for Covid immunizations. . 

Education

MD ( Pediatrics),Bhopal University,1985

MBBS,Bhopal university,1981

Professional Experience

    Academic

  • Mahatma Gandhi institute of Medical Sciences, Sevagram, Lecturer, November 1985 - September 1990
  • Mahatma Gandhi institute of Medical Sciences, Sevagram, Reader, October 1990 - April 1991
  • T N Medical college & BYL Nair Hospital, Mumbai, Associate professor, May 1991 - June 1996
  • T N Medical College &BYL Nair Hospital, Mumbai, Professor, July 1996 - January 2022
  • Seth GS Medical college & KEM Hospital, Mumbai, Professor & Head, February 2011 - February 2022
  • KJ Somaiya Medical college, Mumbai, Professor & head, December 2022 - Present
  • Non Academic

Courses/Subjects Teaching

  • Pediatrics

Research Specialisation

  • Biological and Applied Sciences
  • Nutrition, Health and Medicine

Consultancy Expertise

  • Conducted over 10 industry sponsored clinical drug trials or ICMR sponsored Research studies as Principal/ Co-principal investigators (List as follows) 1. A Prospective, Open-label, Multicenter, Phase 3 Study to Assess the Acceptability of and Adherence to a 10-Day Regimen of Zinc Sulfate Dispersible Tablets for Treatment of Acute Childhood Diarrhea (Sponsored by Ipca Lab, Completed in June 2018) (Principal investigator) 2. A phase III, multicenter, double-blind, randomized study of bovine Rotavirus pentavalent vaccine (BRV-PV) to evaluate lot-to-lot consistency and to investigate potential interference with routine UIP vaccinations in healthy infants in india (Sponsored by SIIL, Completed in 2019) (Principal investigator) 3. A phase III, randomized, open study to assess the immunogenicity, reactogenicity and safety of two different formulations of GlaxoSmithKline (GSK) Biologicals’ oral live attenuated human rotavirus (HRV) vaccine, Rotarix, when given as a two-dose primary vaccination, in healthy infants with no previous history of rotavirus illness or vaccine.(Sponsored by SIIL, Completed in 2021), (Principal investigator) 4. Immunogenicity and Safety of SHAN6® vaccine when administered as booster in healthy toddlers in india (Sponsored by Shantha Biotech, Completed in 2020, (Co-Principal investigator) 5. Immune Lot-to-Lot Consistency and Non-inferiorty of SHAN6TM vaccine in Comparison to SHAN5R+SHANIPVTM When Administered asThree Doses at 6-8, 10-12 and14-16 weeks of age in Healthy indian infants, Concomitantly with Oral Rotavirus Vaccine. (Sponsored by Shantha Biotech, Completed in 2020) (Co-Principal investigator). 6. Efficacy and safety evaluation of Racecadotril in acute watery diarrhea in children (Sponsored by Torrent Pharma, Completed in 2006) (Principal investigator) 7. Clinical evaluation of the efficacy and safety of DRFf/AY/4008 as an appetite stimulant in children with non-pathogenic anorexia (Sponsored by Dabur Pharma, Completed in 2004) (Principal investigator) 8. Cytokine responses to EV71 genotypes in cultured human cells. Sponsored by ICMR-GOI, 2020; in collaboration with Haffkins institute of Virology, Parel (Principal investigator) 9. A Phase IV randomized, controlled study of the safety and immunogenicity of Rabishield + Rabivax S post exposure prophylaxis regimen in patients with potential rabies exposure. (Sponosored by Serum institute of india, 2019 (Co-Principal investigator). 10. A Phase III, open label, randomized, multi-centric, active controlled, clinical trial to evaluate the immune response and safety of SIIPL’s Liquid Live attenuated Human Seasonal Quadrivalent influenza Vaccine (LAIV-LQ) and SIIPL’s Freeze Dried Live attenuated Human Seasonal Trivalent influenza Vaccine (LAIV-FD) among healthy indian individuals > 2 years (Sponosored by Serum institute of india, 2019 (Co-Principal investigator)

Consultancy Projects

  • 1. A Prospective, Open-label, Multicenter, Phase 3 Study to Assess the Acceptability of and Adherence to a 10-Day Regimen of Zinc Sulfate Dispersible Tablets for Treatment of Acute Childhood Diarrhea (Sponsored by Ipca Lab, Completed in June 2018) (Principal investigator)
  • 2. A phase III, multicenter, double-blind, randomized study of bovine Rotavirus pentavalent vaccine (BRV-PV) to evaluate lot-to-lot consistency and to investigate potential interference with routine UIP vaccinations in healthy infants in india (Sponsored by SIIL, Completed in 2019) (Principal investigator)
  • 3. A phase III, randomized, open study to assess the immunogenicity, reactogenicity and safety of two different formulations of GlaxoSmithKline (GSK) Biologicals’ oral live attenuated human rotavirus (HRV) vaccine, Rotarix, when given as a two-dose primary vaccination, in healthy infants with no previous history of rotavirus illness or vaccine.(Sponsored by SIIL, Completed in 2021), (Principal investigator)
  • 4. Immunogenicity and Safety of SHAN6® vaccine when administered as booster in healthy toddlers in india (Sponsored by Shantha Biotech, Completed in 2020, (Co-Principal investigator)
  • 5. Immune Lot-to-Lot Consistency and Non-inferiorty of SHAN6TM vaccine in Comparison to SHAN5R+SHANIPVTM When Administered asThree Doses at 6-8, 10-12 and14-16 weeks of age in Healthy indian infants, Concomitantly with Oral Rotavirus Vaccine. (Sponsored by Shantha Biotech, Completed in 2020) (Co-Principal investigator).
  • 6. Efficacy and safety evaluation of Racecadotril in acute watery diarrhea in children (Sponsored by Torrent Pharma, Completed in 2006) (Principal investigator)
  • 7. Clinical evaluation of the efficacy and safety of DRFf/AY/4008 as an appetite stimulant in children with non-pathogenic anorexia (Sponsored by Dabur Pharma, Completed in 2004) (Principal investigator)
  • 8. Cytokine responses to EV71 genotypes in cultured human cells. Sponsored by ICMR-GOI, 2020; in collaboration with Haffkins institute of Virology, Parel (Principal investigator)
  • 9. A Phase IV randomized, controlled study of the safety and immunogenicity of Rabishield + Rabivax S post exposure prophylaxis regimen in patients with potential rabies exposure. (Sponosored by Serum institute of india, 2019 (Co-Principal investigator).
  • 10. A Phase III, open label, randomized, multi-centric, active controlled, clinical trial to evaluate the immune response and safety of SIIPL’s Liquid Live attenuated Human Seasonal Quadrivalent influenza Vaccine (LAIV-LQ) and SIIPL’s Freeze Dried Live attenuated Human Seasonal Trivalent influenza Vaccine (LAIV-FD) among healthy indian individuals > 2 years (Sponosored by Serum institute of india, 2019 (Co-Principal investigator)

Achievements, Recognitions & Awards

  • • Delivered multiple Orations and Guest lectures at many national/regional conferences
  • • Chairperson, MCGM committee for childhood Immunization for Mumbai since 2014
  • • Member of MCGM- PCPNDT Committee for 2011-2020
  • • Authored over six books including widely acclaimed ‘Textbook of Pediatrics (2017) & “Immunization in Practice” (2021). • Contributed over 15 chapters in reference books on Pediatrics and related subjects. • Published more than 70 research papers in international and national journals. • Presented over 150 research papers in international/national conferences. • Orations, Guest faculty at many national, and regional conferences.
  • • Guided over 70 Postgraduate research projects for MD, DNB, FCPS students. • Conducted as principal/co- investigator over 10 sponsored clinical trials • Ex-Member of the Editorial board, Journal of Postgraduate Medicine, 2013-2016
  • • MCI/NMC Assessor for PG & UG courses since 2008. • Chairperson, MCGM committee for childhood Immunization for Mumbai since 2014. • Chairperson, MCGM-AEFI committee for Covid vaccination, Mumbai since 2020. • Member of MCGM- PCPNDT Committee for 2011-2020 • Ex-Member, Board of studies for Medicine & allied subjects. Mumbai Univ (2005-08). • Ex-Member Trustee of Nair Golden Jubilee Research Foundation, TNMC (2007-2010) • Member of many other institutional Bodies including Ethics Committee (TNMC).
  • • Contributed over 15 chapters in reference books on Pediatrics and related subjects.
  • • Published more than 80 research papers in international and national journals.
  • • Presented over 150 research papers in international/national conferences.

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