Many attempts have been made in recent decades to fight cancer by combining novel technology and traditional approaches. In this article, the applications of nanotechnology were discussed. Nanotechnology has demonstrated extensive applications both in the diagnosis and in treatment of variety of cancers, including improving the selectivity and sensitivity for the treatment of BC. NPs have been able to overcoming the limitations of current medical approaches in many research and clinical trials. For MRI and CT imaging, various metallic NPs are applied as contrast agents, increasing the likelihood of detecting early BC. GNPs’ excellent photothermal properties have contributed to their widespread use in imaging. However, several concerns remain, such as the protection of these NPs, when administrated in the human body. Additional research is required to fully understand the specifics of nanotechnology-based methods, and to develop these NPs as cancer diagnostic tools.