Cancer is a potentially fatal disease caused mainly by environmental factors. Uterine Cancer is the fourth most common cancer among women overall. 19 out of 20 uterine cancers are cancers of the endometrium, the inner lining of the uterus, known as endometrial cancer. The paper gives a detailed study of detection of endometrial cancer using CAD systems& its early diagnosis. The ultrasound image act as an input which is filtered using median filter & then the ROI is segmented using Region Growing Segmentation approach. Then different statistical features are extracted from the ROI which are then used to train the ANN for classification of the Cancer.