Technology disruption, driven by technological advancements like artificial intelligence (AI), blockchain, and big data, is revolutionising industries globally. Organisations must transform by adopting strategic change management, organisational flexibility, and a culture of innovation to counter technological disruptions. This study aims to investigate the role of strategic change management practices in organisational resilience and flexibility in terms of leadership, decision-making, and strategic alignment. Besides, it explores the role performed by innovation culture in establishing organisational resilience to survive and flourish in the rapid digital era. A mixed-methods study was utilised, with quantitative questionnaires and qualitative interviews. Data were collected in 20-30 organisations in three sectors, which are technology, manufacturing, and services. Purposive sampling was utilised by the study with the choice of participants with hands-on experience of digital transformation. Regression and correlation analysis were employed for the analysis of quantitative data, and thematic analysis for analysing the qualitative data. The study confirmed that proactive implementation of digital transformation in organisational strategy was very positively correlated with higher adaptability. Leadership commitment (r = 0.78) and innovation culture (r = 0.82) were key enablers of resilience. Reactive approaches had lower adaptability. The findings highlight leadership and innovation culture as key to achieving successful digital transformation. Companies must foster an enabling culture and corresponding technological plans in line with long-term goals if they are to remain competitive in the digital economy.