The core of this research is whether the technology-based approach has the upper hand over the traditional method of teaching cell structure. The students involved in this research design belong to the age group of 17-18 years old. The research method used in this study is called the “Quasi-experimental method”. In this study, the two divisions of std XII students were involved, where group 1 i.e. students from section A were taught cell biology completely using a technology-based approach, and the teaching methodologies involved infusion of technology in every method executed during the sessions. The second group of students were taught cell biology using a traditional approach. This design aimed to determine the retention rate and depth of understanding, and to conclude whether an infusion of technology gives the upper hand in making concepts crystal clear. This approach was initiated to determine whether the approaches coincide with students' points of view, and if this approach caters to the vast audience. Further reducing the gap that dented understanding by following the traditional approach which is to be refrained and a hybrid approach where the use of technology to track students' progress and level of understanding is to be taken as a vital point in the essence of this research.